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This is a battery-powered device that allows for operant training in an arena, in which mice learn to exert force upon an active force cell to achieve a reward. Two force cells (wheatstone FORCE allows for the frequency, duration, and amplitude of applied force bridges) are monitored and displayed upon an LED screen to be recorded continuously throughout a behavioral experiment. Progressive ratios can be programmed to advance based on any of these three metrics, allowing for operant testing of persistence, vigor, or effort. Force lever readings can be analyzed in tandem with time-locked neural signals including fiber photometry recordings of GCaMP6s fluorescence.
Hackaday: https://hackaday.io/project/163396-force-force-output-of-rodent-calibrated-effort