diff --git a/CHANGELOG.md b/CHANGELOG.md
index 6ce4bb3765..9c4e2c3875 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,5 +1,11 @@
 # Changelog
 
+## Unreleased
+
+### Features
+
+- (snapshots) Compress preprod snapshot manifest with zstd ([#3336](https://github.com/getsentry/sentry-cli/pull/3336))
+
 ## 3.5.1
 
 ### Internal Changes 🔧
diff --git a/Cargo.lock b/Cargo.lock
index 3073b9181f..7fa7281372 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -3702,6 +3702,7 @@ dependencies = [
  "whoami",
  "windows-sys 0.59.0",
  "zip 2.4.2",
+ "zstd",
 ]
 
 [[package]]
diff --git a/Cargo.toml b/Cargo.toml
index 87e4a8f3aa..99092a8382 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -77,6 +77,7 @@ walkdir = "2.3.2"
 which = "4.4.0"
 whoami = "1.5.2"
 zip = "2.4.2"
+zstd = "0.13.3"
 data-encoding = "2.3.3"
 magic_string = "0.3.4"
 chrono-tz = "0.8.4"
diff --git a/src/api/mod.rs b/src/api/mod.rs
index b52d4cc4e0..24a3741844 100644
--- a/src/api/mod.rs
+++ b/src/api/mod.rs
@@ -42,6 +42,7 @@ use symbolic::common::DebugId;
 use symbolic::debuginfo::ObjectKind;
 use url::Url;
 use uuid::Uuid;
+use zstd::Encoder as ZstdEncoder;
 
 use crate::api::errors::{ProjectRenamedError, RetryError};
 use crate::config::{Auth, Config};
@@ -1020,7 +1021,9 @@ impl AuthenticatedApi<'_> {
             PathArg(org),
             PathArg(project)
         );
-        self.post(&path, body)
+        self.request(Method::Post, &path)?
+            .with_zstd_json_body(body)?
+            .send()
     }
 
     /// Fetches upload options for snapshots.
@@ -1360,6 +1363,30 @@ impl ApiRequest {
         Ok(self)
     }
 
+    pub fn with_zstd_json_body<S: Serialize>(mut self, body: &S) -> ApiResult<Self> {
+        let mut encoder = ZstdEncoder::new(Vec::new(), 0)
+            .map_err(|err| ApiError::with_source(ApiErrorKind::CompressionFailed, err))?;
+
+        serde_json::to_writer(&mut encoder, &body).map_err(|err| {
+            let kind = if err.is_io() {
+                ApiErrorKind::CompressionFailed
+            } else {
+                ApiErrorKind::CannotSerializeAsJson
+            };
+            ApiError::with_source(kind, err)
+        })?;
+
+        let compressed = encoder
+            .finish()
+            .map_err(|err| ApiError::with_source(ApiErrorKind::CompressionFailed, err))?;
+
+        debug!("zstd json body: {} bytes compressed", compressed.len());
+        self.body = Some(compressed);
+        self.headers.append("Content-Type: application/json")?;
+        self.headers.append("Content-Encoding: zstd")?;
+        Ok(self)
+    }
+
     pub fn with_body(mut self, body: Vec<u8>) -> Self {
         self.body = Some(body);
         self